Best Data AI skills

Discover AI skills for data analysis, notebooks, ETL, visualization, machine learning and scientific computing.

Looking for the best data skills for Claude Code and other AI coding agents? This collection ranks 134 open-source data skills by a blend of GitHub popularity, licensing clarity, and how well each one documents what it does. Skills — sometimes called Agent Skills — are small, shareable bundles of instructions that an agent loads on demand to become better at a specific job, so a strong data skill can save you from re-explaining the same context in every session. The highest-ranked entries here, including observability-and-instrumentation, html-ppt-weekly-report, html-ppt-zhangzara-long-table, pair an active repository with a real open-source license, which matters if you plan to adapt or redistribute them. Every listing links straight back to its original repository so you can read the source, check recent activity, and copy the exact install command. We refresh this ranking every week as stars, forks, and new releases change across the ecosystem.

Most popular data skills

By GitHub stars.

After you give a substantive answer or draft that the user may act on — advice or recommendations, drafted artifacts such as goals, plans, pitches, proposals, or emails, estimates or projections, analysis or interpretation of data, factual claims they may rely on, or a multi-step argument — invoke this skill BEFORE finalizing your reply and then, if it applies, append 2-3 short follow-up questions, each tied to something specific in what you just produced, that help the user check key facts, probe the reasoning or assumptions, and notice missing context. Do this at most once per conversation. Skip it when the user asked a trivial how-to or simple lookup, wants a purely educational explanation, asked you only to format, convert, or assemble a file from content they provided, is writing code they will run, is doing creative writing or casual chat, or already asked you to double-check, cite, or review — the skill file explains these boundaries and the exact output format.

Official↑ GrowingActive Claude Code
177k GitHub stars Complete terms in LICENSE.txt Updated Sep 10, 2026 Free

Instruments code so production behavior is visible and diagnosable. Use when adding logging, metrics, tracing, or alerting. Use when shipping any feature that runs in production and you need evidence it works. Use when production issues are reported but you can't tell what happened from the available data.

↑ GrowingActive Claude CodeCodexCursor+1
98k GitHub stars MIT Updated Sep 20, 2026 Free

OpenDesign's weekly growth review: stars, installs, activation — the number, the driver, and the recommended move. Built as a decision-grade data & finance deck for growth & product team.

↑ GrowingActive Claude Code
97k GitHub stars Apache-2.0 Updated Sep 21, 2026 Free

OpenDesign's unit-economics and BYOK cost model: the assumptions, the sensitivity, and why it scales. Built as a decision-grade data & finance deck for CFO, investors.

↑ GrowingActive Claude Code
97k GitHub stars Apache-2.0 Updated Sep 21, 2026 Free

Processes and analyzes data with resident-kernel engines (DuckDB, Polars) and one-shot tools. Use for CSV/parquet/JSON analysis, group-by/join/aggregation, time series, distributions, cleaning, or plotting a dataset.

↑ GrowingActive CodexCursorOpenCode
69k GitHub stars Other Updated Sep 21, 2026 Free

Review Archify issues, PRs, or code through value, cost, and impact to support evidence-based maintenance decisions. Use for issue triage, change reviews, and code quality assessments.

NewActive CodexOpenCode
69k GitHub stars MIT Updated Sep 21, 2026 Free

Trending data skills

Gaining the most stars since we started tracking them.

How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

New data skills

Runs MiniMax Code headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to MiniMax Code or obtain a MiniMax-based coding-agent result.

NewActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Look up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), score variants or scan windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and build Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.

↑ GrowingNewActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Runs Qwen Code headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to Qwen Code or obtain a Qwen-based coding-agent result.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Related technologies and use cases

All 133 data skills · 1–60

Instruments code so production behavior is visible and diagnosable. Use when adding logging, metrics, tracing, or alerting. Use when shipping any feature that runs in production and you need evidence it works. Use when production issues are reported but you can't tell what happened from the available data.

↑ GrowingActive Claude CodeCodexCursor+1
98k GitHub stars MIT Updated Sep 20, 2026 Free

OpenDesign's weekly growth review: stars, installs, activation — the number, the driver, and the recommended move. Built as a decision-grade data & finance deck for growth & product team.

↑ GrowingActive Claude Code
97k GitHub stars Apache-2.0 Updated Sep 21, 2026 Free

OpenDesign's unit-economics and BYOK cost model: the assumptions, the sensitivity, and why it scales. Built as a decision-grade data & finance deck for CFO, investors.

↑ GrowingActive Claude Code
97k GitHub stars Apache-2.0 Updated Sep 21, 2026 Free

Review Archify issues, PRs, or code through value, cost, and impact to support evidence-based maintenance decisions. Use for issue triage, change reviews, and code quality assessments.

NewActive CodexOpenCode
69k GitHub stars MIT Updated Sep 21, 2026 Free

Runs Antigravity CLI headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to Antigravity CLI or compare its result with another coding agent.

↑ GrowingActive Claude CodeCodexAntigravity
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs Claude Code non-interactively for code analysis and implementation tasks. Use when the user asks to delegate repository work to Claude Code or compare its result with another coding agent.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs Codex CLI non-interactively for code analysis and implementation tasks. Use when the user asks to delegate repository work to Codex or obtain a second coding-agent result.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs DeepSeek Harness headlessly for bounded repository tasks. Use when the user asks to delegate analysis or implementation to DeepSeek Harness.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs Gemini CLI headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to Gemini CLI or compare its result with another coding agent.

↑ GrowingActive Claude CodeCodexGemini CLI
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs OpenCode non-interactively for repository analysis and coding tasks. Use when the user asks to delegate work to OpenCode or compare OpenCode with another coding agent.

↑ GrowingActive Claude CodeCodexOpenCode
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs Pi non-interactively and parses its JSON event stream for repository tasks. Use when the user asks to delegate a bounded analysis or implementation task to Pi.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs Qwen Code headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to Qwen Code or obtain a Qwen-based coding-agent result.

↑ GrowingActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

Runs MiniMax Code headlessly for repository analysis and coding tasks. Use when the user asks to delegate work to MiniMax Code or obtain a MiniMax-based coding-agent result.

NewActive Claude CodeCodex
52k GitHub stars AGPL-3.0-only Updated Sep 21, 2026 Free

How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Autonomously improve a real artifact (code, training recipe, agent harness, data pipeline, prompt) against an objective and an evaluator, using Hypothesis Tree Refinement (HTR) from the Arbor paper. Use this whenever someone wants to iteratively optimize something over many experiments without overfitting — e.g. "get my model's eval score up", "improve this agent/harness", "tune this pipeline", "beat the baseline on this benchmark", "run a search over approaches and keep the best", "do an MLE-bench / Kaggle-style optimization", or any long-horizon "make this artifact better and don't just memorize the dev set" task. Trigger it even when the user doesn't say "Arbor" or "hypothesis tree" but describes repeated experiment-and-evaluate loops, branching exploration of competing ideas, or worries about a dev/test gap. Runs Claude itself as the coordinator with subagent executors in isolated git worktrees; for the standalone `arbor` CLI tool see references/arbor-upstream.md.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Observe the user's screen via screenpipe, detect repeated research workflows, match them against existing scientific-agent-skills, and draft new skills (or composition recipes that chain existing ones) for the patterns not yet covered. Use when the user asks to analyze their recent work and propose skills based on what they actually do. Requires the screenpipe daemon (https://github.com/screenpipe/screenpipe) running locally on port 3030 — the skill has no other data source and will refuse to run if screenpipe is unreachable. All detection runs locally; only redacted cluster summaries reach the LLM.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Benchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries. Use when automating lab data with benchling-sdk or the v2 API.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Use this skill when working with Brain Imaging Data Structure (BIDS) datasets: organizing neuroscience and biomedical data (MRI, EEG, MEG, iEEG, PET, microscopy, NIRS, motion capture, EMG, MR spectroscopy, behavioral), querying BIDS layouts, validating compliance, converting DICOM to BIDS, writing metadata sidecars, or creating BIDS derivatives.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Unified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API. Best for cross-database analysis, ID mapping across services. For quick single-database lookups use gget; for sequence/file manipulation use biopython.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

End-to-end bulk RNA-seq orchestrator — takes raw FASTQ reads through QC and trimming (FastQC, fastp/Trim Galore), alignment and quantification (STAR, Salmon, featureCounts), assembles a gene-level counts matrix, then hands off to differential expression (pydeseq2), pathway/GSEA enrichment (pathway-enrichment), and publication figures (scientific-visualization). Use whenever the user has bulk RNA-seq reads or quant output and wants a complete, reproducible differential-expression workflow — e.g. "analyze my RNA-seq", "FASTQ to DESeq2", "run nf-core/rnaseq", "STAR/Salmon quantification", "build a counts matrix for DESeq2", or "go from reads to differentially expressed genes and enriched pathways". Routes between an nf-core/rnaseq (Nextflow) path and a standalone STAR/Salmon path, and covers experimental design, strandedness, and QC gates. For single-cell RNA-seq use the scanpy skill instead.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Look up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), score variants or scan windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and build Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.

↑ GrowingNewActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Query the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data. Use when you need population-scale cell metadata, gene expression slices, Census summary counts, source H5AD URIs/downloads, embeddings, spatial Census data, or reference atlas comparisons across organisms, tissues, diseases, assays, and cell types. For analyzing your own local single-cell data use scanpy, anndata, or scvi-tools.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Google quantum computing framework. Use when targeting Google Quantum AI hardware, designing noise-aware circuits, or running quantum characterization experiments. Best for Google hardware, noise modeling, and low-level circuit design. For IBM hardware use qiskit; for quantum ML with autodiff use pennylane; for physics simulations use qutip.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Comprehensive citation management for academic research. Search OpenAlex, PubMed, and Google Scholar for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to BibTeX, or ensure reference accuracy in scientific writing.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Prepare and validate research-only clinical decision-support evaluation, evidence-profile, cohort, survival, biomarker/model, privacy, and governance artifacts. Use for aggregate or synthetic research documentation and traceability—not patient care or live clinical operation.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Create safety-bounded draft structures and run local deterministic checks for clinical case, diagnostic, trial, safety, and aggregate research reports. Use only with synthetic, de-identified, or aggregate inputs and verified source-fact manifests; every output requires qualified review.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Run a multi-perspective Mind Council deliberation on any question, decision, or creative challenge. Use this skill whenever the user wants diverse viewpoints, needs help making a tough decision, asks for a council/panel/board discussion, wants to explore a problem from multiple angles, requests devil's advocate analysis, or says things like "what would different experts think about this", "help me think through this from all sides", "council mode", "mind council", or "deliberate on this". Also trigger when the user faces a dilemma, trade-off, or complex choice with no obvious answer.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Distributed computing for larger-than-RAM pandas/NumPy workflows. Use when you need to scale existing pandas/NumPy code beyond memory or across clusters. Best for parallel file processing, distributed ML, integration with existing pandas code. For out-of-core analytics on single machine use vaex; for in-memory speed use polars.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Query documented public database APIs with explicit endpoints, filters, pagination, and provenance. Use when a scientific, regulatory, financial, or other database-backed fact must be retrieved reproducibly from a named source rather than inferred from general knowledge.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Molecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity) with traditional ML or GNNs when you want extensive featurization options and MoleculeNet benchmarks. Best for quick experiments with pre-trained models, diverse molecular representations. For graph-first PyTorch workflows use torchdrug; for benchmark datasets use pytdc.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Generate transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Use when you need spatial gene expression in log1p-CPM for 224x224 tiles at about 20x, want to query protein-coding genes by symbol instead of a fixed panel, or want to run prediction across a whole slide after tiling with histolab.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Transform data into compelling narratives using visualization, context, and persuasive structure. Use when presenting analytics to stakeholders, creating data reports, or building executive presentations.

↑ Growing Claude CodeCodexCursor+3
39k GitHub stars MIT Updated Aug 24, 2026 Free

Creates, manages, and queries Arize datasets and examples. Covers dataset CRUD, appending examples, exporting data, and file-based dataset creation using the ax CLI. Use when the user needs test data, evaluation examples, or mentions create dataset, list datasets, export dataset, append examples, dataset version, golden dataset, or test set.

Official GitHub Copilot
38k GitHub stars MIT Updated Aug 18, 2026 Free

Generates deep links to the Arize UI for traces, spans, sessions, datasets, labeling queues, evaluators, and annotation configs. Produces clickable URLs for sharing Arize resources with team members. Use when the user wants to link to or open a trace, span, session, dataset, evaluator, or annotation config in the Arize UI.

Official GitHub Copilot
38k GitHub stars MIT Updated Aug 18, 2026 Free

Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Extract cognitive patterns and thinking fingerprints from any text. Use this skill when the user wants to analyze how someone thinks, understand cognitive style, profile writing or speech patterns, compare thinking styles between people, asks "what's my thinking style", "analyze how this person reasons", "cognitive profile", "thinking pattern", "DHDNA", "digital DNA", or wants to understand the mind behind any text. Also trigger when the user provides text and wants deeper insight into the author's reasoning patterns, decision-making style, or cognitive signature.

34k GitHub stars MIT Updated Aug 17, 2026 Free

DiffDock and DiffDock-L molecular docking. Use for protein-small-molecule pose prediction from PDB or sequence plus SMILES/SDF/MOL2, batch docking, virtual screening, and pose-confidence interpretation. Not for binding affinity prediction.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Build and operate reproducible genomics workloads on DNAnexus with the dx CLI, dxpy, apps/applets, native workflows, dxCompiler, and Nextflow. Use for DNAnexus data transfers, dxapp.json development, execution monitoring, workflow import, and project automation.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files) or Word templates (.dotx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', '.dotx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx or .dotx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Use when working directly with the `esm` Python SDK, ESM3 or ESMC model IDs, Forge/Biohub inference clients, or ESMFold2 folding workflows.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Analyze, manipulate, compare, annotate, and visualize phylogenetic or other hierarchical trees with ETE 4. Use for Newick/Nexus tree I/O, topology edits and pattern matching, Robinson-Foulds comparisons, gene-tree evolutionary events and reconciliation, NCBI/GTDB taxonomy, SmartView exploration, and publication rendering. Do not use it to infer trees from raw sequences; align sequences and infer a tree first.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Web toolkit powered by Exa, tuned for scientific and technical content. Use this skill when the user needs to search the web or fetch/extract URL content. Covers: web search (semantic lookups, research, current info — with optional research-paper category and academic domain filtering) and URL extraction (fetching pages, articles, academic PDFs in batch). Use this skill for web-related tasks when the user wants high-quality search or scholarly filtering via category=research paper. Triggers on requests to search, look up, fetch a page, or extract an article.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Design experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls, factorial or fractional-factorial designs, design of experiments (DOE), screening many factors, response-surface optimization, crossover or repeated-measures or split-plot designs, cluster/group randomization, Latin squares, plate layouts, batch/run-order effects, replication vs. pseudoreplication, or sequential/adaptive/group-sequential designs. Trigger even for informal phrasings like "how should I set up this experiment", "how do I avoid confounding", "what's the best way to test these 6 factors", or "assign these mice to conditions". For computing the sample size or power once the design is chosen, use statistical-power; for analyzing data already collected, use statistical-analysis.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Perform bounded, local exploratory analysis of explicitly supported scientific files. Use for redacted CSV/TSV/JSON profiles; optional NumPy, HDF5, FASTA/FASTQ, and basic image metadata inspection; missingness/leakage audits; outlier and transformation sensitivity; and rigorous EDA report scaffolds. Other domain formats are reference-only and unknown formats fail closed.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Read, inspect, and write Flow Cytometry Standard (FCS) 2.0, 3.0, and 3.1 files with FlowIO. Use for low-level FCS metadata and channel inspection, NumPy event extraction, multi-dataset files, table export, and FCS 3.1 creation; use FlowKit for compensation, cytometry transforms, gating, or FlowJo workspaces.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Plan, configure, inspect, restart, and analyze bounded FluidSim computational-fluid-dynamics simulations with explicit numerical-validity and HPC safety checks. Use for FluidSim solver selection, parameter review, FFT/MPI setup, output diagnostics, or restart compatibility.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Generate or edit images with AI models through the OpenRouter Image API (Gemini, Seedream, Recraft, GPT-Image, Riverflow). Use for photos, illustrations, artwork, concept art, visual assets, logos, and image editing or compositing from reference images. For flowcharts, circuits, pathways, and other technical diagrams, use the scientific-schematics skill instead.

34k GitHub stars MIT Updated Aug 17, 2026 Free

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 170,000+ scientists worldwide. 158 ready-to-use skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

Claude CodeCodexCursor+1
32k GitHub stars MIT Updated Jul 29, 2026 Free

Perform cohort analysis on user engagement data — retention curves, feature adoption trends, and segment-level insights. Use when analyzing user retention by cohort, studying feature adoption over time, investigating churn patterns, or identifying engagement trends.

Claude Code
25k GitHub stars MIT Updated Jul 3, 2026 Free

Generate realistic dummy datasets for testing with customizable columns, constraints, and output formats (CSV, JSON, SQL, Python script). Use when creating test data, building mock datasets, or generating sample data for development and demos.

Claude Code
25k GitHub stars MIT Updated Jul 3, 2026 Free

Custom skills

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Frequently asked questions

What can data skills do?
Guide an agent through analysis workflows: loading and cleaning data, running notebooks, building charts and reporting results with the caveats a careful analyst would include.
How many data skills are there?
AISkillsify lists 133 data skills, refreshed weekly from public GitHub repositories. They are ranked by a quality score and GitHub popularity; the most popular, trending and newest are highlighted above.