Overview
esm is an open-source data skill for Claude Code and compatible agents, published by K-Dense-AI. Its author describes it as: “Use when working directly with the `esm` Python SDK, ESM3 or ESMC model IDs, Forge/Biohub inference clients, or ESMFold2 folding workflows.”. The project has 34k stars on GitHub and is available under the MIT license. Add it to your setup with `git clone https://github.com/K-Dense-AI/scientific-agent-skills ~/.claude/skills/esm`.
What esm does
ESM provides protein language models for understanding, generating, and designing proteins. Use this skill for current EvolutionaryScale/Biohub workflows: ESM3 for generative design, ESMC for representation learning and embeddings, hosted Forge/Biohub inference, and ESMFold2 all-atom structure prediction.
What’s inside
The SKILL.md for esm is organised into these sections:
- Overview
- Core Capabilities
- 1. Protein Sequence Generation with ESM3
- 2. Structure Prediction and Inverse Folding
- 3. Protein Embeddings with ESM C
- 4. Function Conditioning and Annotation
- 5. Chain-of-Thought Generation
- 6. Batch Processing with Forge API
- Model Selection Guide
- Installation
- Authentication
- Common Workflows
Installation
Add esm to your agent with:
git clone https://github.com/K-Dense-AI/scientific-agent-skills ~/.claude/skills/esmReview a skill’s source before installing it — skills can instruct your agent to run commands. This command comes from the skill’s public repository, which is the source of truth for setup steps. New to skills? Read how to install Claude Code skills.
Supported agents
Neither the skill nor its repository names a specific agent. It uses the SKILL.md format, which several agents can load — check the repository for any agent-specific requirements.
License
esm is published under the MIT license.
Strengths
- Clear MIT license — safe to read and adapt within its terms
- Ships in K-Dense-AI/scientific-agent-skills, an established project with 33,821 GitHub stars
- Actively maintained — repository updated in the last 90 days
Author
Topics
Frequently asked questions
- What does esm do?
- Use when working directly with the `esm` Python SDK, ESM3 or ESMC model IDs, Forge/Biohub inference clients, or ESMFold2 folding workflows.
- How do I install esm?
- Run git clone https://github.com/K-Dense-AI/scientific-agent-skills ~/.claude/skills/esm in your agent, then reload your skills. Review the source at https://github.com/K-Dense-AI/scientific-agent-skills before installing.
- Is esm free to use?
- Yes. esm is free and open source under the MIT license, so you can read, run, and adapt it within that license's terms.
- Where does esm come from?
- esm ships inside K-Dense-AI/scientific-agent-skills, a repository that contains 42 catalogued skills in total. The repository's 33,821 GitHub stars apply to that whole collection, not to this skill on its own.