AI skills — page 4

1,482 open-source skills for Claude Code, Codex, Cursor, Gemini CLI and other AI agents. Search by technology or use case, filter by agent and category, and sort by stars, activity or momentum.

1,482 skills · showing 181–240

Fetch any X/Twitter post as clean LLM-friendly JSON. Converts x.com, twitter.com, or adhx.com links into structured data with full article content, author info, and engagement metrics. No scraping or browser required.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

This skill should be used when the user asks to "implement LLM-as-judge", "compare model outputs", "create evaluation rubrics", "mitigate evaluation bias", or mentions direct scoring, pairwise comparison, position bias, evaluation pipelines, or automated quality assessment.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Advogado criminalista especializado em Maria da Penha, violencia domestica, feminicidio, direito penal brasileiro, medidas protetivas, inquerito policial e acao penal.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Advogado especialista em todas as areas do Direito brasileiro: familia, criminal, trabalhista, tributario, consumidor, imobiliario, empresarial, civil e constitucional.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Autonomous DevSecOps & FinOps Guardrails. Orchestrates Gemini 3 Flash to audit Linux Kernel patches, Terraform cost drifts, and K8s compliance.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Evaluate agent behavior with versioned cases and explicit verifiers. Use when comparing agent or prompt changes, reproducing failures, or running agent regression tests.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

A hybrid memory system that provides persistent, searchable knowledge management for AI agents (Architecture, Patterns, Decisions).

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Memory is the cornerstone of intelligent agents. Without it, every interaction starts from zero. This skill covers the architecture of agent memory: short-term (context window), long-term (vector stores), and the cognitive architectures that organize them.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Optimize multi-agent systems with coordinated profiling, workload distribution, and cost-aware orchestration. Use when improving agent performance, throughput, or reliability.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Meta-skill que orquestra todos os agentes do ecossistema. Scan automatico de skills, match por capacidades, coordenacao de workflows multi-skill e registry management.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Tools are how AI agents interact with the world. A well-designed tool is the difference between an agent that works and one that hallucinates, fails silently, or costs 10x more tokens than necessary. This skill covers tool design from schema to error handling.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Orchestrate autonomous AI development pipelines through your Kanban board (Asana, GitHub Projects, Linear). Manages multi-worker Claude Code dispatch, deterministic quality gates, adversarial review, per-task cost tracking, and crash-proof pipeline execution.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Audits GitHub Actions workflows for security vulnerabilities in AI agent integrations including Claude Code Action, Gemini CLI, OpenAI Codex, and GitHub AI Inference. Detects attack vectors where attacker-controlled input reaches. AI agents running in CI/CD pipelines.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Email infrastructure for AI agents. Create accounts, send/receive emails, manage webhooks, and check karma balance via the AgentMail API.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Build AI phone agents with AgentPhone API. Use when the user wants to make phone calls, send/receive SMS, manage phone numbers, create voice agents, set up webhooks, or check usage — anything related to telephony, phone numbers, or voice AI.

↑ GrowingActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Create, edit, validate, and run Agent QA tests, suites, and hooks through MCP or CLI while preserving canonical IDs and schema contracts.

↑ GrowingActive Claude CodeCodexCursor+1
47k GitHub stars MIT Updated Sep 21, 2026 Free

Debug, patch, and verify failed Agent QA runs from MCP evidence, artifacts, logs, and local code without hiding product or infrastructure defects.

↑ GrowingActive Claude CodeCodexCursor+1
47k GitHub stars MIT Updated Sep 21, 2026 Free

Triage failed Agent QA runs with MCP evidence, artifacts, logs, fixed failure categories, confidence, and actionable next steps.

↑ GrowingActive Claude CodeCodexCursor+1
47k GitHub stars MIT Updated Sep 21, 2026 Free

Use when summarizing agent evaluations where autonomous, assisted, failed, timed-out, or invalid outcomes must remain distinct and comparable.

↑ GrowingActive Claude CodeCodexCursor+1
47k GitHub stars MIT Updated Sep 21, 2026 Free

Use when an agent workflow needs deterministic recovery evidence for sandbox, MCP/tool, worker, checkpoint, memory, or orchestration failures.

↑ GrowingActive Claude CodeCodexCursor+1
47k GitHub stars MIT Updated Sep 21, 2026 Free

Conduct periodic access reviews and certifications. Implement access governance and recertification workflows. Use when managing access compliance.

NewActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Build automated evaluation suites for AI agents using golden datasets, rubrics, and regression gates. Use when shipping agent features, validating prompt changes, or gating deployments on quality.

NewActive Claude CodeCodexCursor+2
47k GitHub stars MIT Updated Sep 21, 2026 Free

Create, revise, or audit AGENTS.md files from repository evidence, verified commands, and correctly scoped instructions without overwriting maintainer intent.

↑ GrowingActive Claude CodeCodexCursor+2
46k GitHub stars MIT Updated Sep 14, 2026 Free

Build container-based Foundry Agents with Azure AI Projects SDK (ImageBasedHostedAgentDefinition). Use when creating hosted agents with custom container images in Azure AI Foundry.

↑ GrowingActive Claude CodeCodexCursor+2
46k GitHub stars MIT Updated Sep 14, 2026 Free

Generate project-specific AGENTS.md and companion rules by analyzing a codebase. Supports full, minimal, update, and dry-run modes with package-manager detection, monorepos, backups, managed blocks, confidence scoring, and command validation.

↑ GrowingActive Claude CodeCodexCursor+2
46k GitHub stars MIT Updated Sep 14, 2026 Free

How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Autonomously improve a real artifact (code, training recipe, agent harness, data pipeline, prompt) against an objective and an evaluator, using Hypothesis Tree Refinement (HTR) from the Arbor paper. Use this whenever someone wants to iteratively optimize something over many experiments without overfitting — e.g. "get my model's eval score up", "improve this agent/harness", "tune this pipeline", "beat the baseline on this benchmark", "run a search over approaches and keep the best", "do an MLE-bench / Kaggle-style optimization", or any long-horizon "make this artifact better and don't just memorize the dev set" task. Trigger it even when the user doesn't say "Arbor" or "hypothesis tree" but describes repeated experiment-and-evaluate loops, branching exploration of competing ideas, or worries about a dev/test gap. Runs Claude itself as the coordinator with subagent executors in isolated git worktrees; for the standalone `arbor` CLI tool see references/arbor-upstream.md.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Observe the user's screen via screenpipe, detect repeated research workflows, match them against existing scientific-agent-skills, and draft new skills (or composition recipes that chain existing ones) for the patterns not yet covered. Use when the user asks to analyze their recent work and propose skills based on what they actually do. Requires the screenpipe daemon (https://github.com/screenpipe/screenpipe) running locally on port 3030 — the skill has no other data source and will refuse to run if screenpipe is unreachable. All detection runs locally; only redacted cluster summaries reach the LLM.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Benchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries. Use when automating lab data with benchling-sdk or the v2 API.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Use this skill when working with Brain Imaging Data Structure (BIDS) datasets: organizing neuroscience and biomedical data (MRI, EEG, MEG, iEEG, PET, microscopy, NIRS, motion capture, EMG, MR spectroscopy, behavioral), querying BIDS layouts, validating compliance, converting DICOM to BIDS, writing metadata sidecars, or creating BIDS derivatives.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Unified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API. Best for cross-database analysis, ID mapping across services. For quick single-database lookups use gget; for sequence/file manipulation use biopython.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

End-to-end bulk RNA-seq orchestrator — takes raw FASTQ reads through QC and trimming (FastQC, fastp/Trim Galore), alignment and quantification (STAR, Salmon, featureCounts), assembles a gene-level counts matrix, then hands off to differential expression (pydeseq2), pathway/GSEA enrichment (pathway-enrichment), and publication figures (scientific-visualization). Use whenever the user has bulk RNA-seq reads or quant output and wants a complete, reproducible differential-expression workflow — e.g. "analyze my RNA-seq", "FASTQ to DESeq2", "run nf-core/rnaseq", "STAR/Salmon quantification", "build a counts matrix for DESeq2", or "go from reads to differentially expressed genes and enriched pathways". Routes between an nf-core/rnaseq (Nextflow) path and a standalone STAR/Salmon path, and covers experimental design, strandedness, and QC gates. For single-cell RNA-seq use the scanpy skill instead.

↑ GrowingActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Look up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), score variants or scan windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and build Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.

↑ GrowingNewActive
46k GitHub stars MIT Updated Sep 21, 2026 Free

Audit local AI coding-agent sessions with agenttrace for cost, tool failures, latency, anomalies, health, diffs, and CI gates.

↑ Growing Claude CodeCodexCursor+2
45k GitHub stars MIT Updated Aug 17, 2026 Free

AI agent development workflow for building autonomous agents, multi-agent systems, and agent orchestration with CrewAI, LangGraph, and custom agents.

↑ Growing Claude CodeCodexCursor+2
45k GitHub stars MIT Updated Aug 17, 2026 Free

Query the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data. Use when you need population-scale cell metadata, gene expression slices, Census summary counts, source H5AD URIs/downloads, embeddings, spatial Census data, or reference atlas comparisons across organisms, tissues, diseases, assays, and cell types. For analyzing your own local single-cell data use scanpy, anndata, or scvi-tools.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Google quantum computing framework. Use when targeting Google Quantum AI hardware, designing noise-aware circuits, or running quantum characterization experiments. Best for Google hardware, noise modeling, and low-level circuit design. For IBM hardware use qiskit; for quantum ML with autodiff use pennylane; for physics simulations use qutip.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Comprehensive citation management for academic research. Search OpenAlex, PubMed, and Google Scholar for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to BibTeX, or ensure reference accuracy in scientific writing.

↑ GrowingActive
45k GitHub stars MIT Updated Sep 14, 2026 Free

Expert in designing and building autonomous AI agents. Masters tool use, memory systems, planning strategies, and multi-agent orchestration.

↑ Growing Claude CodeCodexCursor+2
45k GitHub stars MIT Updated Aug 10, 2026 Free

Search 8,400+ AI and ML jobs across 489 companies, inspect listings and employers, match roles, and view salary and market stats via AI Dev Jobs MCP

↑ Growing Claude CodeCodexCursor+1
45k GitHub stars MIT Updated Aug 10, 2026 Free

Build production-ready LLM applications, advanced RAG systems, and intelligent agents. Implements vector search, multimodal AI, agent orchestration, and enterprise AI integrations.

Claude CodeCodexCursor+2
44k GitHub stars MIT Updated Jul 31, 2026 Free

AAS Core is the local, agent-first control plane for complete catalog discovery, agent-owned selection, stack validation, and planning, backed by 1,987+ agentic skills. Includes CLI, local MCP, catalog, plugins, and Workbench.

Claude CodeCodexCursor+2
44k GitHub stars MIT Updated Jul 29, 2026 Free

Prepare and validate research-only clinical decision-support evaluation, evidence-profile, cohort, survival, biomarker/model, privacy, and governance artifacts. Use for aggregate or synthetic research documentation and traceability—not patient care or live clinical operation.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Create safety-bounded draft structures and run local deterministic checks for clinical case, diagnostic, trial, safety, and aggregate research reports. Use only with synthetic, de-identified, or aggregate inputs and verified source-fact manifests; every output requires qualified review.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Run a multi-perspective Mind Council deliberation on any question, decision, or creative challenge. Use this skill whenever the user wants diverse viewpoints, needs help making a tough decision, asks for a council/panel/board discussion, wants to explore a problem from multiple angles, requests devil's advocate analysis, or says things like "what would different experts think about this", "help me think through this from all sides", "council mode", "mind council", or "deliberate on this". Also trigger when the user faces a dilemma, trade-off, or complex choice with no obvious answer.

↑ GrowingActive
44k GitHub stars MIT Updated Sep 7, 2026 Free

Generate professional resumes that conform to the Reactive Resume schema. Use when the user wants to create, build, or generate a resume through conversational AI, or asks about resume structure, sections, or content. This skill guides the agent to ask clarifying questions, avoid hallucination, and produce valid JSON output for https://rxresu.me.

↑ GrowingActive
42k GitHub stars MIT Updated Aug 28, 2026 Free

Distributed computing for larger-than-RAM pandas/NumPy workflows. Use when you need to scale existing pandas/NumPy code beyond memory or across clusters. Best for parallel file processing, distributed ML, integration with existing pandas code. For out-of-core analytics on single machine use vaex; for in-memory speed use polars.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Query documented public database APIs with explicit endpoints, filters, pagination, and provenance. Use when a scientific, regulatory, financial, or other database-backed fact must be retrieved reproducibly from a named source rather than inferred from general knowledge.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Molecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity) with traditional ML or GNNs when you want extensive featurization options and MoleculeNet benchmarks. Best for quick experiments with pre-trained models, diverse molecular representations. For graph-first PyTorch workflows use torchdrug; for benchmark datasets use pytdc.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

Generate transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Use when you need spatial gene expression in log1p-CPM for 224x224 tiles at about 20x, want to query protein-coding genes by symbol instead of a fixed panel, or want to run prediction across a whole slide after tiling with histolab.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free

NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.

↑ GrowingActive
40k GitHub stars MIT Updated Aug 31, 2026 Free
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